BIO-IDENTICAL hormones are plant based hormones structurally similar to natural hormones of estrogen and progesterone. They work to alleviate certain symptoms of menopause such as hot flashes, vaginal dryness, pain with intercouse and insomnia. Most Bio-identical Hormone replacement is given in the form of a cream so that the hormones are absorbed effectively through the skin. Hormones that are routinely prescribed in menopause can include Estrogen, Progesterone and Testosterone.